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KMID : 0617219910020010085
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Duksung Bulletin Phamaceutical Sciences
1991 Volume.2 No. 1 p.85 ~ p.89
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Studies on the Production of Anthraquinone Devivatives by Tissue Culture Rubia Species
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Shin Soon-Hee
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Abstract
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The tissue culture of Rubia cordifolia var. pratensis and R. akane were performed to enhance the biosynthesis of anthraquinone pigments under various conditions. The production of alizarin and purpurin in the callus was separately analysed and quantitatively compared. The pigment bioosynthesis was more active in the callus from R. cordifolia var. pratensis than from R. akane. The addition of α-ketoglutaric acid, a biosynthetic precursor of antraquinones, enhanced the production of alizarin and purpurin remarkably.
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